![]() ![]() We provide detailed circuits consisting of neurons and their chemical synapses for most of the central brain. We define cell types, refine computational compartments, and provide an exhaustive atlas of cell examples and types, many of them novel. Improved methods include new procedures to prepare, image, align, segment, find synapses in, and proofread such large data sets. We summarize new methods and present the circuitry of a large fraction of the brain of the fruit fly Drosophila melanogaster. The neural circuits responsible for animal behavior remain largely unknown. Department of Zoology, University of Cambridge, United Kingdom.Institute of Zoology, Biocenter Cologne, University of Cologne, Germany.MRC Laboratory of Molecular Biology, United States. ![]() Institute for Quantitative Biosciences, University of Tokyo, Japan.Google Research, Google LLC, Switzerland.Life Sciences Centre, Dalhousie University, Canada.Janelia Research Campus, Howard Hughes Medical Institute, United States. ![]()
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